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George Biondi was one of Enrico Balazar's men. He was killed in the firefight between Balazar and Roland Deschain and Eddie Dean.

Biondi was responsible for the heroin shot that caused Henry Dean to overdose. They were playing Trivial Pursuit at The Leaning Tower while waiting for Eddie's return.

Biondi reappears in Wolves of the Calla. Attempting to persuade Calvin Tower to sell the Vacant Lot to the Sombra Corporation. During the discussion, Eddie Dean enters New York City through the Unfound Door, enters the storage area and attacks Biondi and Jack Andolini.

Biondi's final appearance in Song of Susannah is in a general store where Eddie shoots him in the head.